High blood sugar and oral treatment
When diagnosed with high blood sugar without ketoacidosis or hyperosmolar symptoms treatment with high dose oral medication may work and lessen the need for insulin therapy.
In an article in J. Clin Endocriology from jan 2016 100 persons with high blood sugar were put on 2 regimens of peroral drugs:
1. Glipizide 10mg extended release tablet.
2. 5mg Saxagliptin and 2000 mg of metformin.
Median fasting blood sugar was 19 mmol/L and A1C 11%
All patients rec. general info and were followed up in a diabetic center.
Nearly all pat. got better values and median fasting was 7.2 mmol/L and A1C 7%
Frequency of hypoglycemia was higher in the glipizide group but in neither were there serious sequelae or sugar under 2.8.