In Journal Watch april 2017 the effects og Testosterone gel on deficient men with symptoms provided no effect on cognition. Effect on coronary artery plaques: median noncalcified plaque volume increased significantly in the testo group.

Another randomized trial looking at anaemia and testo treatment increased Hb significantly in users. Might low testo be a cause of anaemia in some older men where another reason was not found?

Another T trial measured bone density and found significant increases but was to short to assess fracture risk.

Another industry funded Testo trial with about 300 men treated for 3 years changes in carotid intima-media thickness and coronary calcium score were similar in treatment and placebo group. Concerning muscle performance: chest-press but not leg-press strength increased. The difference was small and clinical meaningfulnes remains unclear.

A previous report on sexual function showed modest effect on sexual function.